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DeCS
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Descriptor English:
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Autophagy-Related Protein 5
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Descriptor Spanish:
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Proteína 5 Relacionada con la Autofagia
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Descriptor Portuguese:
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Proteína 5 Relacionada à Autofagia
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Synonyms English:
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ATG-5 Protein
ATG5 Protein
Apoptosis-Specific Protein
Autophagy Protein-5
Autophagy-Related 5 Protein
ATG 5 Protein
Apoptosis Specific Protein
Autophagy Protein 5
Autophagy Related 5 Protein
Autophagy Related Protein 5
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Tree Number:
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D12.776.094.250
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Definition English:
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An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56557
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Unique Identifier:
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D000071187
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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